Phthalates

Introduction

Characteristic of the Agent

Fate and Transport

Environmental Impacts

Environmental Monitoring

Exposure Pathway

Routes of Exposure

Methods for Measuring Human Exposure

Strategies for Preventing or Controlling Exposures


Harmful Effects

Dose Response

Absorption, Distribution and Metabolism

Biomarkers

Target Organs and Tissues

Mechanisms of Toxicity

Risk Assessment and Risk Management

References

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Exposure Pathway

Phthalates are composed of many compound forms. Phthalate exposure occurs in much of our everyday life, used in countless numbers of different products.
The following are the compounds and their common uses.XI

Diethyl phthalate (DEP) - Industrial solvent used in many consumer products, mostly in those containing fragrances. Products include perfume, cologne, bar soap, shampoo and hand lotion.

Dibutyl phthalate (DBP) - Industrial solvent used in products such as nail polish, cosmetics and insecticides.

Benzylbutyl phthalate (BzBP) - Industrial solvent used in products such as adhesives, sealants, cosmetics and car-care products.

Dicyclohexyl phthalate (DCHP) - Used primarily in research laboratories




Di-2-ethylhexyl phthalate (DEHP) - Primarily used to produce flexible plastics (PVC tubing, Blood bags). Formally used in children’s toys and food packaging in the U.S.

Di-n-octyl phthalate (DOP) - Primarily used in flexible plastics

Di-isononyl phthalate (DINP) - Primarily used to produce flexible plastics.