Acrylamide

Characteristics

Uses

Environmental Transport

Environmental Deposition

Methods for Monitoring in the Environment

Methods for Monitoring Human Exposure

Safeguards Against Acrylamide Exposure


Harmful Effects

Dose Response

Absorption, Distribution and Metabolism

Primary Sites for Toxicity

Biomarkers

Mechanism of Action

Risk Assessment and Management

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Acrylamide Policy

Introduction to Policy

Decision Makers and Stakeholders

Current Policy

Policy Recommendations


References

THE ISSUE FACING POLICY-MAKERS

Since acrylamide was discovered in food, there has been a rapid response by agencies worldwide. Previous and still present issue with acrylamide is deciding the level of carcinogenicity. Acrylamide has many uses, however very little conclusive research was done prior to its discovery in food in 2001. Currently the EPA has a standard for acrylamide, has a water treatment technique and mandates that a public warning is issued to alert sensitive population if acrylamide is used in water treatment.

However, the recent discovery of acrylamide formation in food has caused renewed interest in acrylamide as a potential carcinogen although it has also has neurological, developmental, reproductive, testicular, and DNA effects. There has been no recommended diet change due to acrylamide since no risk assessment has been done and acrylamide is found in so many staple foods. There is also the issue on how much information should be brought to the public’s attention. (52)

A lot of the research at present involves reducing the amount of acrylamide in food as opposed to changing the diet to exclude foods that are potentially high in acrylamide. There is also interest in quantifying the amount of acrylamide in the diet and the amount formed during domestic cooking. The formation of acrylamide from sugars and amino acids is still being studied although a lot has been found in the past two years.

Many of the committees formed include those by World Health Organization (WHO) and the Food and Agriculture Organization (FAO) of the United Nations feel that acrylamide is a serious problem. They all conclude that not enough information is known to make a recommendation